Scalable near-real-time Bayesian phylogenetics for outbreaks with Delphy

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11012-6Delphy makes near-real-time and scalable Bayesian phylogenetics possible for growing viral outbreaks, enabling public health bodies anywhere to analyse and reac…

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11012-6

Delphy makes near-real-time and scalable Bayesian phylogenetics possible for growing viral outbreaks, enabling public health bodies anywhere to analyse and react to their own data with state-of-the-art accuracy and minimal friction.

Tumour cells shape their environment to protect them from the immune system

Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02703-1A subset of pancreatic cancer cells express the genes SERPINE1 or SERPINB2, which form a molecular mesh around them. This sticky matrix helps to retain immunosu…

Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02703-1

A subset of pancreatic cancer cells express the genes SERPINE1 or SERPINB2, which form a molecular mesh around them. This sticky matrix helps to retain immunosuppressive cells and exclude the immune cells that kill cancer cells. Disrupting this process in mice improves immune control of pancreatic tumours and sensitizes them to immunotherapy.

Human brain cells transplanted into mice in ‘most extensive’ integration ever

Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02912-8Lab-grown organoids wire into mice missing a key part of their brain, offering a new way to test drugs for developmental conditions.

Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02912-8

Lab-grown organoids wire into mice missing a key part of their brain, offering a new way to test drugs for developmental conditions.

Targeted genomic integration and rearrangement using prime assembly

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11024-2Prime assembly enables RNA-guided integration of medium-to-large DNA sequences in human cells without requiring double-strand breaks or cell cycle progression, …

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11024-2

Prime assembly enables RNA-guided integration of medium-to-large DNA sequences in human cells without requiring double-strand breaks or cell cycle progression, and supports exon recoding, transgene insertion and megabase-scale rearrangements.

Molecular-level observation of the self-assembly of a virus-like particle

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-10948-zUsing mass photometry combined with a single-molecule trapping method allows real-time monitoring of the assembly of individual virus-like particles with molecu…

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-10948-z

Using mass photometry combined with a single-molecule trapping method allows real-time monitoring of the assembly of individual virus-like particles with molecular resolution, enabling observation and quantification of their self-assembly pathways and dynamics.

Nearly one in seven young, male white voters in the US support white nationalism

Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02648-5Three national surveys reveal how factors such as gender, age, political alignment and income are correlated with support for white nationalism in the United St…

Nature, Published online: 16 September 2026; doi:10.1038/d41586-026-02648-5

Three national surveys reveal how factors such as gender, age, political alignment and income are correlated with support for white nationalism in the United States.

Heterogeneous photonic integration of single-crystalline nanomembranes

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11000-wA framework consisting of advanced epitaxy and layer lift-off techniques uses heterogeneous photonic integration of single-crystalline nanomembranes to infuse d…

Nature, Published online: 16 September 2026; doi:10.1038/s41586-026-11000-w

A framework consisting of advanced epitaxy and layer lift-off techniques uses heterogeneous photonic integration of single-crystalline nanomembranes to infuse desired functionalities into silicon and silicon nitride photonics, demonstrating ultraefficient electro-optical and magneto-optical modulation.